CYP2D6 copy number variation (CNV) detection is a critical aspect of PGx testing. However, not all CYP2D6 alleles are functionally similar. Depending on ethnicity, up to 45% of individuals possess non-functional CYP2D6/CYP2D7 “hybrid alleles” including exon 9 exchanges, *13 and *68. Many detection technologies cannot detect these alleles, resulting in sample mischaracterization.
The VeriDose CYP2D6 Panel accurately detects CNVs even in the presence of difficult to detect hybrid alleles. It interrogates 22 points in 7 regions of the CYP2D6 gene using a single well. This panel can be run simultaneously with genotyping panels, seamlessly integrating genotyping and CNV workflows.
|Product||# of Samples||Format||Catalog #|
|VeriDose CYP2D6 CNV Panel Set – CPM (2x96)||192||96 CPM||13372F|
|VeriDose CYP2D6 CNV Panel Set – CPM (10x96)||960||96 CPM||13360F|
|VeriDose CYP2D6 CNV Panel Set – CPM (2x384)||768||384 CPM||13362D|
|VeriDose CYP2D6 CNV Panel Set – CPM (10x384)||3,840||384 CPM||13361D|
|VeriDose CYP2D6 CNV Panel 2N Control||200||N/A||02005|