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Liquid Biopsy

Ultra-sensitivity at a low cost

Sensitivity and coverage for disease monitoring with cfDNA

Disease progression and resistance monitoring studies require low cost detection without sacrificing sensitivity. The MassARRAY® System can detect variants as low as 0.1% allele frequency at a low cost, making it ideally suited for disease monitoring.

While liquid biopsies provide easier access to tumor cells and DNA, they don’t necessarily provide enough. With just a few copies of circulating tumor DNA (ctDNA) per mL of plasma, you cannot afford to run multiple tests to detect all emerging resistance markers. The multiplexing capability of the UltraSEEK® chemistry makes it easy to detect over 100 variants, including insertions and deletions, using cfDNA from a single blood draw.

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Sample Requirements

Use DNA isolated from a variety of samples including blood plasma, circulating cell-free DNA and circulating tumor cells.

DNA Input
per reaction:

≥10 ng or ≥3,300 copies of amplifiable template
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Custom Assay Design

Getting started doesn’t have to be difficult. Get up and running quickly with the content you need. Create your own custom panels or let Assays by Agena scientists design, develop and functionally verify custom research use assays for you. Assays can be developed for targeted germline or somatic genotyping, translocations, copy number variants and more.

Learn About Custom Assays

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