High resolution quantitative methylation profiling
Rapidly analyze methylation status of 10s to 100s of samples using the MassARRAY System.
MassCLEAVETM chemistry enables high-resolution, quantitative methylation profiling using base-specific cleavage on bisulfite-converted DNA. The high sensitivity of the MassARRAY System enables detection of differences as low as 5% between methylated and non-methylated DNA.
Custom panels for profiling CpG methylation can be designed using Agena’s EpiDesigner software. General reagents including bisulfite conversion kits are available to process samples for analysis on the MassARRAY system.
Excerpt from Quantitative Region-Specific DNA Methylation Analysis by the EpiTYPER Technology, DNA Methylation Protocols. Humana Press, NY NY, 2018
Get up and running quickly with the content you need. Our Assays by Agena scientists design, develop and functionally verify custom research use assays. Assays can be developed for targeted CpG methylation profiling.