An open platform for blood group typing
Blood group antigen genotyping, an attractive and transformative alternative to classical serology, is gaining rapid acceptance in immunohematology laboratories. Agena Bioscience® provides a comprehensive collection of ready-to-use genotyping assays for extended antigen typing of erythrocytes, platelets, and neutrophils.
Our technology involves multiplex end-point PCR and single base primer extension followed by precise detection and automated measurement with the MassARRAY® System. Hemo ID® software converts assigned genotypes into predicted phenotypes and enables data visualization and custom report generation.
Publication: High-throughput Kell, Kidd, and Duffy matrix-assisted laser desorption/ionization, time-of-flight mass spectrometry–based blood group genotyping of 4000 donors shows close to full concordance with serotyping and detects new alleles
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Assays by Agena scientists design, develop and functionally verify custom research use assays. Assays can be developed for targeted germline or somatic genotyping, translocations, copy number variants and methylation profiling.